Feedback repression of polyamine uptake into mammalian cells requires active protein synthesis

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy.

Anthony E. Pegg · PubMed · 1988 · 1.5K citations

Chemoprevention Strategy, Pathology, Pharmaceutical Chemistry +18

Interference with polyamine biosynthesis and/or function by analogs of polyamines or methionine as a potential anticancer chemotherapeutic strategy.

Porter Cw, Sufrin · PubMed · 1986 · 184 citations

Pharmaceutical Science, Chemoprevention Strategy, Pharmacotherapy +16

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone)

Leena Alhonen‐Hongisto, Pauli Seppänen, Juhani Jänne · Biochemical Journal · 1980 · 182 citations · Full text

Spermatogenesis, Transport System, Culture Medium +16

Role of antizyme in degradation of ornithine decarboxylase in HTC cells

Yasuko Murakami, Shinichi Hayashi · Biochemical Journal · 1985 · 128 citations · Full text

Aldehyde Dehydrogenase, Htc Cells, Biochemistry +14

Characterization of the polyamine transport system in mouse neuroblastoma cells. Effects of sodium and system A amino acids.

Clifford A. Rinehart, Kuang Yu Chen · Journal of Biological Chemistry · 1984 · 111 citations · Full text

Polyamine Transport, Neurotransmitter, Cellular Pharmacology +18