The Proapoptotic Protein tBid Forms Both Superficially Bound and Membrane-Inserted Oligomers

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Damage +12

Structural chemistry and molecular biology

Alexander Rich, Norman Davidson, Linus Pauling · Medical Entomology and Zoology · 1968 · 1.7K citations

Structure Determination, Structure Elucidation, Structural Biology +1

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

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Mitochondrial Apoptosis, Mitochondrial Function, Apoptosis +9

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

Tomomi Kuwana, Mason Mackey, Guy Perkins et al. · Cell · 2002 · 1.5K citations · Full text

Proteinlipid Interaction, Biochemistry, Natural Sciences +7

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

Michael Certo, Victoria Del Gaizo Moore, Mari Nishino et al. · Cancer Cell · 2006 · 1.2K citations · Full text

Death Signals, Mitophagy, Cellular Addiction +10