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Specific Filaggrin Mutations Cause Ichthyosis Vulgaris and Are Significantly Associated with Atopic Dermatitis in Japan

Toshifumi Nomura, Masashi Akiyama, Aileen Sandilands, Ikue Nemoto‐Hasebe, Kaori Sakai, Akari Nagasaki, Mitsuhito Ota, Hiroo Hata, Alan Evans, Hiroshi Shimizu,

Journal of Investigative Dermatology · 2008 · 147 citations · 14 references

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Diagnostic Features of Atopic Dermatitis

Jon M. Hanifin, Georg Rajka · Acta Dermato Venereologica · 1980 · 5.1K citations · Full text

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Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao et al. · Nature Genetics · 2006 · 3K citations

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Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris

Frances J.D. Smith, Alan D. Irvine, Ana Terron-Kwiatkowski et al. · Nature Genetics · 2006 · 1K citations

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Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema

Aileen Sandilands, Ana Terron-Kwiatkowski, Peter Hull et al. · Nature Genetics · 2007 · 664 citations

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Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations

Stephan Weidinger, Thomas Illig, Hansjörg Baurecht et al. · Journal of Allergy and Clinical Immunology · 2006 · 611 citations

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