Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>

Shohei Hori, Takashi Nomura, Shimon Sakaguchi · Science · 2003 · 8K citations

Lymphocyte Development, Genetics, T-regulatory Cell +24

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.6K citations

Lymphocyte Development, T-regulatory Cell, Immunology +9

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

Lu Zhang, Jianghao Xu, Xuan Zhang et al. · Cellular Physiology and Biochemistry · 2017 · 4.1K citations · Full text

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.3K citations

Autoimmune Disease, Disease Mechanism, Genetic Disorder +12

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

Mary E. Brunkow, Eric W. Jeffery, Kathryn A. Hjerrild et al. · Nature Genetics · 2001 · 2.6K citations

New Forkhead/winged-helix Protein, Immunology, Pathology +6