Simultaneous analysis of mitragynine, 7-hydroxymitragynine, and other alkaloids in the psychotropic plant “kratom” (Mitragyna speciosa) by LC-ESI-MS

Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hayato Ishikawa et al. · Life Sciences · 2004 · 232 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Antinociceptive action of mitragynine in mice: Evidence for the involvement of supraspinal opioid receptors

Kinzo Matsumoto, Maho Mizowaki, Thongpradichote Suchitra et al. · Life Sciences · 1996 · 152 citations

Medicine, Pharmacology, Neuropharmacology +13

Identification of opioid receptor subtypes in antinociceptive actions of supraspinally-admintstered mitragynine in mice

Thongpradichote Suchitra, Kinzo Matsumoto, Michihisa Tohda et al. · Life Sciences · 1998 · 136 citations

Medicine, Neuroscience, Pharmacology +16

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hiromitsu Takayama et al. · Life Sciences · 2005 · 115 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Involvement of μ-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa

Kenjiro Matsumoto, Yoshio Hatori, Toshihiko Murayama et al. · European Journal of Pharmacology · 2006 · 100 citations

Medicine, Medicinal Chemistry, Pharmacology +15