Syunji Horie

Studies on the Synthesis and Opioid Agonistic Activities of Mitragynine-Related Indole Alkaloids:  Discovery of Opioid Agonists Structurally Different from Other Opioid Ligands

Hiromitsu Takayama, Hayato Ishikawa, Mika Kurihara et al. · Journal of Medicinal Chemistry · 2002 · 264 citations · Full text

Medicinal Chemistry, Mitragyna Speciosa, Pharmacological Study +13

Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hayato Ishikawa et al. · Life Sciences · 2004 · 224 citations

Medicinal Chemistry, Pharmacological Study, Pain Medicine +10

Inhibitory effect of mitragynine, an alkaloid with analgesic effect from thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig ileum through the opioid receptor

Kazuo Watanabe, Shingo Yano, Syunji Horie et al. · Life Sciences · 1997 · 120 citations

Isolated Guinea-pig Ileum, Pharmacological Study, Pain Medicine +10

Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa

Leonardo T. Yamamoto, Syunji Horie, Hiromitsu Takayama et al. · General Pharmacology The Vascular System · 1999 · 117 citations

Pharmacological Study, Medicine, Mitragynine Pseudoindoxyl +7

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa

Kenjiro Matsumoto, Syunji Horie, Hiromitsu Takayama et al. · Life Sciences · 2005 · 112 citations

Medicinal Chemistry, Pharmacological Study, Medicine +8