Examination of the Functional Activity of P-glycoprotein in the Rat Placental Barrier Using Rhodamine 123

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

Carlos Cordon‐Cardo, James P. O’Brien, João Paulo Boccia et al. · Journal of Histochemistry & Cytochemistry · 1990 · 1.1K citations

Medicine, Tumor Expression, Pharmacology +15

Expression of P-glycoprotein in Human Placenta: Relation to Genetic Polymorphism of the Multidrug Resistance (MDR)-1 Gene

Mizuho Tanabe, Ichiro Ieiri, Naoki Nagata et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 535 citations

Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure

Johan W. Smit, Maarten T. Huisman, Olaf van Tellingen et al. · Journal of Clinical Investigation · 1999 · 355 citations · Full text

Genetics, Fetal Medicine, Gynecology +22

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

George R. Lankas, L. David Wise, Mark E. Cartwright et al. · Reproductive Toxicology · 1998 · 310 citations

Embryology, Developmental Biology, Medicine +11

Transplacental Uptake of Glucose Is Decreased in Embryonic Lethal Connexin26-deficient Mice

Heinz‐Dieter Gabriel, Dirk Jung, C Bützler et al. · The Journal of Cell Biology · 1998 · 292 citations · Full text

Genetics, Transplacental Uptake, Cellular Physiology +16