Concepedia

Ras Activated ERK and PI3K Pathways Differentially Affect Directional Movement of Cultured Fibroblasts

Leandra Sepe, Maria Carla Ferrari, Concita Cantarella, Francesca Fioretti, Giovanni Paolella

Cellular Physiology and Biochemistry · 2013 · 26 citations · 41 references

DOIFull text

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Abstract

Ras is greatly involved in determining and regulating directionality, ERK is its key effector for starting, driving and regulating directional movement.

References

41

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ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

Emmanuel Vial, Erik Sahai, Christopher J. Marshall · Cancer Cell · 2003 · 408 citations · Full text

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Goodness-of-fit tests on a circle. II

G. S. Watson · Biometrika · 1962 · 402 citations

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Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

Atsuo T. Sasaki, Cheryl Chun, Kosuke Takeda et al. · The Journal of Cell Biology · 2004 · 369 citations · Full text

Goodness-of-fit tests on a circle

G. S. Watson · Biometrika · 1961 · 362 citations

, , +10