Emmanuel Vial

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

Emmanuel Vial, Erik Sahai, Christopher J. Marshall · Cancer Cell · 2003 · 410 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +12

Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility

Erik Sahai, Raquel García-Medina, Jacques Pouysségur et al. · The Journal of Cell Biology · 2006 · 187 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Elevated ERK-MAP kinase activity protects the FOS family member FRA-1 against proteasomal degradation in colon carcinoma cells

Emmanuel Vial, Christopher J. Marshall · Journal of Cell Science · 2003 · 142 citations

Life Sciences, Molecular Biology, Oncology +17

Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy

Ilya Chumakov, Aude Milet, Nathalie Cholet et al. · Orphanet Journal of Rare Diseases · 2014 · 105 citations · Full text

Medicine, Neurology, Pharmacology +15

Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene

Jacques Aubert, David Piwnica, Béatrice Bertino et al. · British Journal of Dermatology · 2018 · 72 citations

Medicine, Dermatology, Pharmacology +16