Resolution of racemic carbovir and selective inhibition of human immunodeficiency virus by the (−) enantiomer

New Soluble-Formazan Assay for HIV-1 Cytopathic Effects: Application to High-Flux Screening of Synthetic and Natural Products for AIDS-Antiviral Activity

O. S. Weislow, Rebecca Kiser, Donald L. Fine et al. · JNCI Journal of the National Cancer Institute · 1989 · 691 citations

Public Health, Infectious Diseases, Hiv Control +7

Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides

Robert Vince, Hua Mei · Journal of Medicinal Chemistry · 1990 · 305 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Potent and selective activity of a new carbocyclic nucleoside analog (Carbovir: NSC 614846) against human immunodeficiency virus In vitro

Robert Vince, Hua Mei, Jay Brownell et al. · Biochemical and Biophysical Research Communications · 1988 · 231 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

E. Lucile White, William B. Parker, Lisa J. Macy et al. · Biochemical and Biophysical Research Communications · 1989 · 100 citations

Life Sciences, Biology, Molecular Biology +14

Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine

Jan Balzarini, H. Baumgartner, Michael Bodenteich et al. · Journal of Medicinal Chemistry · 1989 · 46 citations

Medicine, Chemistry, Medicinal Chemistry +8