Essential Role of Ubiquitin and TSG101 Protein in Formation and Function of the Central Supramolecular Activation Cluster

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

Arash Grakoui, Shannon K. Bromley, Cenk Sumen et al. · Science · 1999 · 3.1K citations

Three-dimensional segregation of supramolecular activation clusters in T cells

Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer et al. · Nature · 1998 · 2.3K citations

Signal Transduction, Cell Division, Cell Interaction +6

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

Zuoming Sun, Chris Arendt, Wilfried Ellmeier et al. · Nature · 2000 · 888 citations

Inflammation, Adaptive Immune System, Immunology +10

T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster

Rajat Varma, Gabriele Campi, Tadashi Yokosuka et al. · Immunity · 2006 · 864 citations · Full text

Signal Transduction, Tumor Microenvironment, Cell Interaction +8

AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

Bettina Strack, Arianna Calistri, Stewart Craig et al. · Cell · 2003 · 813 citations · Full text

Binding Partner, Virus Budding, Molecular Virology +9