Increasing-current electroshock seizure test: A new method for assessment of anti- and pro-convulsant activities of drugs in mice

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Public Health, Biostatistics, Pharmacology +12

Antiepileptic Drug Development: II. Anticonvulsant Drug Screening

Ronald L Krall, J. K. Penry, B. G. White et al. · Epilepsia · 1978 · 823 citations

Medicine, Pharmacology, Clinical Pharmacology +12

The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models

Wolfgang Löscher, C. P. Fassbender, Björn Nolting · Epilepsy Research · 1991 · 340 citations

Medicine, Neuroscience, Pharmacology +12

A Facilitation Action of Reserpine on the Central Nervous System

G. Chen, Charles R. Ensor, Barbara Bohner · Experimental Biology and Medicine · 1954 · 190 citations

Medicine, Neuroscience, Pharmacology +13

Spontaneous epileptic seizures and electroencephalographic changes in the course of phenothiazine therapy

John Logothetis · Neurology · 1967 · 154 citations

Medicine, Neurology, Pharmacology +16