High Levels of Tumor Necrosis Factor-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

Life Sciences, Bioinformatics, Oncology +12

TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

Jonathan Lam, Sunao Takeshita, Jane E. Barker et al. · Journal of Clinical Investigation · 2000 · 1.4K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Tumor Necrosis Factor α Stimulates Osteoclast Differentiation by a Mechanism Independent of the Odf/Rankl–Rank Interaction

Kanichiro Kobayashi, Naoyuki Takahashi, Eijiro Jimi et al. · The Journal of Experimental Medicine · 2000 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +17

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK

Marieke Essers, Sanne Weijzen, Alida M.M. de Vries-Smits et al. · The EMBO Journal · 2004 · 795 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Osteoclasts: What Do They Do and How Do They Do It?

Steven L. Teitelbaum · American Journal Of Pathology · 2007 · 717 citations · Full text

Medicine, Orthopaedic Surgery, Bone Metabolism +7