Effects of histone deacetylase inhibitors on transcriptional regulation of the hsp70 gene in Drosophila

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

Functional Genomics, Engineering, Medicine +12

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Karolin Luger, Armin W. Mäder, Robin K. Richmond et al. · Nature · 1997 · 9.3K citations

Nucleosome Core Particle, Crystal Structure, Engineering +10

The language of covalent histone modifications

Brian D. Strahl, C. David Allis · Nature · 2000 · 8.5K citations

Histone Modifications, Chromatin, Chromatin Remodeling +7

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

Toshio Tsukiyama, Peter B. Becker, Carl Wu · Nature · 1994 · 668 citations

Chromatin, Transcriptional Regulation, Heat-shock Promoter +10

Studies of the DNA binding properties of histone H4 amino terminus. Thermal denaturation studies reveal that acetylation markedly reduces the binding constant of the H4 “tail” to DNA.

Liang Hong, Gary P. Schroth, H.R. Matthews et al. · Journal of Biological Chemistry · 1993 · 422 citations · Full text

Histone Modifications, Protein Assembly, Epigenetic Change +23