Morphological and functional alterations of the cochlea in apolipoprotein E gene deficient mice

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

Andrew Plump, Jonathan D. Smith, Tony Hayek et al. · Cell · 1992 · 2.2K citations

Metabolic Syndrome, Lipid Disorder, Oxysterol +12

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

Sunny H. Zhang, Robert L. Reddick, Jorge A. Piedrahita et al. · Science · 1992 · 2.2K citations

Vascular Disease, Pathology, Hyperlipidemia +17

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

Yutaka Nakashima, Andrew Plump, Elaine W. Raines et al. · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1994 · 1.7K citations

Vascular Disease, Apoe-deficient Mice, Pathology +20

Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.

Andreas M. Zeiher, H. Drexler, H. Wollschläger et al. · Circulation · 1991 · 993 citations

Vascular Disease, Selective Endothelial Dysfunction, Cardiovascular Function +17

Quantitative assessment of atherosclerotic lesions in mice

Beverly Paigen, A. W. Morrow, Patricia A. Holmes et al. · Atherosclerosis · 1987 · 954 citations

Vascular Disease, Cardiovascular Disease, Pathology +6