Simultaneous determination of methotrexate and its eight metabolites in human whole blood by capillary zone electrophoresis

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

Carmen J. Allegra, Bruce A. Chabner, J C Drake et al. · Journal of Biological Chemistry · 1985 · 333 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Carmen J. Allegra, J C Drake, Jacques Jolivet et al. · Proceedings of the National Academy of Sciences · 1985 · 313 citations · Full text

Medicine, Oncology, Pharmacology +7

Basic and Clinical Pharmacology

Howard S. Pitkow · JAMA · 1983 · 272 citations

Medicine, Anesthesiology, Pharmacology +8

Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

Hao Zeng, Zhe‐Sheng Chen, Martin G. Belinsky et al. · PubMed · 2001 · 257 citations

Medicine, Biochemistry, Pharmacology +12

Human thymidylate synthetase—III

Daniel W. Szeto, Yung-Chi Cheng, A. Rosowsky et al. · Biochemical Pharmacology · 1979 · 63 citations