An Isotopic Assay for Thymidylate Synthetase^*

DeWayne Roberts

Biochemistry

Altmetric Attention ScoreMolecular BiologyBibliometricsChemical BiologyBiochemistry 1966 +21

Polyglutamyl Derivatives of Folate as Substrates and Inhibitors of Thymidylate Synthetase

Roy L. Kisliuk, Y. Gaumont, Charles M. Baugh

Journal of Biological Chemistry

BiosynthesisEngineeringBiotransformationBiochemistryNatural Sciences +11

Transport Energetics of the Folic Acid Analogue, Methotrexate, in L1210 Leukemia Cells

I. David Goldman

Journal of Biological Chemistry

Energy MetabolismEnergy-dependent TransportBiochemistryMedicineFolic Acid Analogue +13

Cell killing studies on the mode of action of methotrexate on L-cells in vitro.

J. Borsa, G. F. Whitmore

PubMed

Purine SynthesisMtx DisruptionMedicineImmunologyCell Death +10

On the nature of a transport alteration determining resistance to amethopterin in the L1210 leukemia.

Francis M. Sirotnak, Soji Kurita, Dorris J. Hutchison

PubMed

L1210 LeukemiaMixed-phenotype Acute LeukemiaMichaelis-menten KineticsChemical BiologyCellular Physiology +16

Human thymidylate synthetase. II. Derivatives of pteroylmono- and -polyglutamates as substrates and inhibitors.

Bruce J. Dolnick, Y. C. Cheng

Journal of Biological Chemistry

Medicinal ChemistryBiosynthesisDerivativesBiochemistryNatural Sciences +8

Modes of uptake of methotrexate by normal and leukemic human leukocytes in vitro and their relation to drug response.

David Kessel, Thomas C. Hall, DeWayne Roberts

PubMed

Therapeutic Drug MonitoringPharmacokinetic ModelingGranulocyteMedicineImmunology +12

Studies on γ-glutamyl carboxypeptidase I. The solid phase synthesis of analogs of polyglutamates of folic acid and their effects on human liver γ-glutamyl carboxypeptidase

Charles M. Baugh, James C. Stevens, Carlos L. Krumdieck

Biochimica et Biophysica Acta (BBA) - Enzymology

Biochemistryγ-Glutamyl CarboxypeptidaseSolid Phase SynthesisFolic AcidPharmacology +2

Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization.

Bruce J. Dolnick, Y. C. Cheng

Journal of Biological Chemistry

ImmunologyMolecular BiologyThymidylate SynthetaseChemical BiologyEnzymatic Modification +16

Inhibition of thymidylate synthetase and dihydrofolate reductase by naturally occurring oligoglutamate derivatives of folic acid.

Morris Friedkin, Laurence T. Plante, Elizabeth J. Crawford, +1

Journal of Biological Chemistry

Medicinal ChemistryBioorganic ChemistryAldo-keto ReductaseBiochemistryAldehyde Dehydrogenase +13