Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

Nm Taxol, Cell Death, Cell Culture +17

Paclitaxel-resistant Human Ovarian Cancer Cells Have Mutant β-Tubulins That Exhibit Impaired Paclitaxel-driven Polymerization

Paraskevi Giannakakou, Dan L. Sackett, Yoon‐Koo Kang et al. · Journal of Biological Chemistry · 1997 · 681 citations · Full text

Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome

Timothy D. Howard, William A. Paznekas, Eric D. Green et al. · Nature Genetics · 1997 · 654 citations

Mendelian Disorder, Genetic Disorder, Genetics +4

Mutations of the TWIST gene in the Saethre-Chotzene syndrome

Vincent El Ghouzzi, M Le Merrer, Fabienne Perrin‐Schmitt et al. · Nature Genetics · 1997 · 642 citations

Mendelian Disorder, Genetic Disorder, Genetics +4

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

Maria Kavallaris, Dennis Yi‐Shin Kuo, Catherine A. Burkhart et al. · Journal of Clinical Investigation · 1997 · 594 citations · Full text

Class Iii, Gynecology, Specific Beta-tubulin Isotypes +16