Identification of the Human Cytochromes P450 Responsible for Atomoxetine Metabolism

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

Preparation and Properties of Partially Purified Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome P-450 Reductase from Rabbit Liver Microsomes

Theodore A. van der Hoeven, Minor J. Coon · Journal of Biological Chemistry · 1974 · 519 citations · Full text

Rabbit Liver Microsomes, Fatty Liver Disease, Fatty Acids +16

Isolation and Characterization of Human Liver Cytochrome P450 2C19: Correlation between 2C19 and S-Mephenytoin 4′-Hydroxylation

Steven Wrighton, Jeffrey Stevens, Gerald W. Becker et al. · Archives of Biochemistry and Biophysics · 1993 · 283 citations

Molecular Pharmacology, S-mephenytoin 4′-Hydroxylation, Hepatology +10

A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain.

David T. Wong, Penny G. Threlkeld, Kevin L. Best et al. · Journal of Pharmacology and Experimental Therapeutics · 1982 · 192 citations · Full text

Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: Effects on coumarin, dicumarol, and testosterone oxidation

Robin E. Pearce, Denise Greenway, Andrew Parkinson · Archives of Biochemistry and Biophysics · 1992 · 189 citations

Biochemistry, Medicine, Liver Physiology +8