Nucleosides and Nucleotides · 1999 · 13 citations · 7 references
Life SciencesChemical BiologyMolecular BiologyEpigeneticsNucleic Acid BiochemistryNucleic Acid ChemistryBase PairingDna ChemistryDna StabilityDna StructureNucleic Acid StructureOligonucleotide ChemistryComplementary Base PairingDeoxyribonucleic Acid (Dna) StructureDna Base PairingNucleic Acid Base PairingPurine Chemistry
Abstract Parallel-stranded (ps) oligonucleotide duplexes containing several new base pairs formed between 7-deazaisoguanine and cytosine, 8-aza-7-deaza-isoguanine and cytosine, and 5-aza-7-deaza guanine and guanine are described. The stability of the pshybrids increased if the duplex contains 8-aza-7-deazaisoguanine instead of isoguanine and is decreased by 7-deazaisoguanine incorporation. The purine-purine base pair between 5-aza-7-deazaguanine and guanine was found to be more stable than that of 5-methylisocytosine with guanine.
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F. Morvan, Bernard Rayner, Jean‐Louis Imbach et al. · Nucleic Acids Research · 1986 · 98 citations · Full text