Frank Seela

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

Saeko Mizusawa, Susumu Nishimura, Frank Seela · Nucleic Acids Research · 1986 · 699 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

Syn-anti conformational analysis of regular and modified nucleosides by 1D 1H NOE difference spectroscopy: a simple graphical method based on conformationally rigid molecules

Helmut Rosemeyer, Gábor K. Tóth, Bożenna Golankiewicz et al. · The Journal of Organic Chemistry · 1990 · 151 citations

Natural Sciences, Chemistry, Organic Chemistry +12

Modification of DNA with Octadiynyl Side Chains: Synthesis, Base Pairing, and Formation of Fluorescent Coumarin Dye Conjugates of Four Nucleobases by the Alkyne−Azide “Click” Reaction

Frank Seela, Venkata Ramana Sirivolu, Padmaja Chittepu · Bioconjugate Chemistry · 2007 · 142 citations

Pharmacy, Biochemistry, Molecular Biology +17

Cyclohexene Nucleic Acids (CeNA):  Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

Jing Wang, Birgit Verbeure, Ingrid Luyten et al. · Journal of the American Chemical Society · 2000 · 137 citations

Life Sciences, Biochemistry, Molecular Biology +17

1′, 5′ ‐Anhydrohexitol Oligonucleotides: Synthesis, Base Pairing and Recognition by Regular Oligodeoxyribonucleotides and Oligoribonucleotides

Chris Hendrix, Helmut Rosemeyer, Ilse Verheggen et al. · Chemistry - A European Journal · 1997 · 135 citations

Life Sciences, Biochemistry, Molecular Biology +17