Concepedia

Prevention of Ocular Inflammation in Endotoxin-Induced Uveitis with Resveratrol by Inhibiting Oxidative Damage and Nuclear Factor–κB Activation

Shunsuke Kubota, Toshihide Kurihara, Hiroshi Mochimaru, Shingo Satofuka, Kousuke Noda, Yoko Ozawa, Yuichi Oike, Susumu Ishida, Kazuo Tsubota

Investigative Ophthalmology & Visual Science · 2009 · 155 citations · 41 references

DOI

Abstract

Resveratrol prevented EIU-associated cellular and molecular inflammatory responses by inhibiting oxidative damage and redox-sensitive NF-kappaB activation.

References

41

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

Meishiang Jang, Lining Cai, George Udeani et al. · Science · 1997 · 4.9K citations

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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Konrad T. Howitz, Kevin J. Bitterman, Haim Cohen et al. · Nature · 2003 · 3.7K citations

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Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.6K citations · Full text

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

Jason G. Wood, Blanka Rogina, Siva Lavu et al. · Nature · 2004 · 1.9K citations

, , +7

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne, Philip Lambert, Simon Schenk et al. · Nature · 2007 · 1.7K citations · Full text

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