Concepedia
PLoS ONE · 2010 · 28 citations · 38 references
Open access
clinicaltrials.gov; Registration numbers NCT00090896 and NCT00471887.
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New Guidelines to Evaluate the Response to Treatment in Solid Tumors
Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations
World Health Organization, Solid Tumors, Cancer Management +17
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
Elizabeth Tivol, Frank Borriello, Alain Schweitzer et al. · Immunity · 1995 · 2.9K citations · Full text
Lymphoid Neoplasia, Autoimmune Disease, Immunology +6
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
Hironori Ueda, Joanna M. M. Howson, Laura Esposito et al. · Nature · 2003 · 2.2K citations · Full text
Immunogenetics, Autoimmune Disease, T-regulatory Cell +9
CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms
Richard V. Parry, Jens M. Chemnitz, Kenneth A. Frauwirth et al. · Molecular and Cellular Biology · 2005 · 1.9K citations · Full text
Distinct Mechanisms, T-regulatory Cell, Immunology +19
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
Giao Q. Phan, James Chih‐Hsin Yang, Richard M. Sherry et al. · Proceedings of the National Academy of Sciences · 2003 · 1.6K citations · Full text