The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki, +22

Nature Medicine

Insulin ResistanceMetabolic SyndromeObesityMetabolic DisorderBiochemistry +9

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat, +6

Nature

Insulin ResistanceMetabolic SyndromeObesityBody CompositionMedicine +8

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki, +10

Nature

Metabolic SyndromeNutritionEnergy MetabolismBile AcidsEnergy Homeostasis +10

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

Norikazu Maeda, Iichiro Shimomura, Ken Kishida, +16

Nature Medicine

ObesityMetabolic SyndromeDiabetesPhysiologyDiet-induced Insulin Resistance +5

Leptin Inhibits Bone Formation through a Hypothalamic Relay

Patricia Ducy, Michael Amling, Shu Takeda, +7

Cell

SclerostinPhysiologyHypothalamic PeptideHypothalamic RelayNervous System +4

Increased bone formation in osteocalcin-deficient mice

Patricia Ducy, Christelle Desbois, Brendan F. Boyce, +9

Nature

Orthopaedic SurgeryOsteoarthritisOsteogenesisBone HomeostasisBone Formation +4

Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo

Hyo‐Jeong Kim, Takamasa Higashimori, So‐Young Park, +7

Diabetes

ImmunologyIl-6 TreatmentInsulin SignalingInflammationMetabolic Syndrome +18

Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

Monzur Murshed, Thorsten Schinke, Marc D. McKee, +1

The Journal of Cell Biology

SclerostinGlycobiologyGla-containing ProteinsCell GrowthCellular Physiology +21

Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice

Cédric Le May, Khoi Chu, Min Hu, +5

Proceedings of the National Academy of Sciences

Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth

Jake A. Kushner, Maria A. Ciemerych, Ewa Sicińska, +5

Molecular and Cellular Biology

Cell ProliferationCell CyclePancreas TransplantationGlucose ToleranceCellular Physiology +18