Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

Michelle S. Rhyu, Lily Yeh Jan, Yuh Nung Jan · Cell · 1994 · 764 citations

Developmental Biology, Cell Division, Numb Protein +8

<i>Polo</i>, a mitotic mutant of <i>Drosophila</i> displaying abnormal spindle poles

Cláudio E. Sunkel, David M. Glover · Journal of Cell Science · 1988 · 561 citations

Aberrant Activation of Notch Signaling in Human Breast Cancer

Spyros Stylianou, Robert B. Clarke, Keith Brennan · Cancer Research · 2006 · 556 citations

Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells

Joerg Betschinger, Karl Mechtler, Juergen A. Knoblich · Cell · 2006 · 518 citations · Full text

Cell Lineage, Developmental Biology, Cell Division +9

Asymmetric segregation of Numb and Prospero during cell division

Juergen A. Knoblich, Lily Yeh Jan, Yuh Nung Jan · Nature · 1995 · 499 citations

Cell Division, Asymmetric Segregation, Cell Interaction +3