Organic Letters · 2006 · 18 citations · 27 references
PharmacyChemistryMedicinal ChemistryNatural Product BiosynthesisOrganic ChemistrySynthetic Medicinal ChemistryConjugation ReactionsDiversity-oriented SynthesisHeterocycle SynthesisOrganic SynthesisRetrosynthetic AnalysisPyrrolidine Synthesis
[Structure: see text] An advanced intermediate in our planned synthesis of mitomycin C has been acquired in nine steps from tert-butyl glyoxylate. The aziridinyl pyrrolidine and quinone subunits are coupled regioselectively to arrive at an enamine that is prepared for C10 homologation.
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Catalytic asymmetric synthesis
Choice Reviews Online · 2001 · 2.7K citations
An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes
S. Müller, Bernd Liepold, Gerald J. Roth et al. · Synlett · 1996 · 776 citations