Publication | Closed Access
A chemical epigenetics approach for engineering the in situbiosynthesis of a cryptic natural product from Aspergillus niger
197
Citations
9
References
2008
Year
EngineeringSecondary MetaboliteBiosynthesisMetabolic EngineeringNatural Product BiosynthesisPathway EngineeringChemical Epigenetics MethodologyBiotransformationCryptic Natural ProductBiochemistryChemical Epigenetics ApproachMetabolomicsFungal Cell FactoryBiomolecular EngineeringAspergillus NigerBiotechnologyGenetic EngineeringSynthetic BiologyMicrobiology-One CoreMedicine
A new fungal metabolite, nygerone A (), featuring a unique 1-phenylpyridin-4(1H)-one core that had previously not been reported from any natural source, has been obtained from Aspergillus niger using a chemical epigenetics methodology.
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