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Identification of trans-4-[1-[[7-fluoro-2-(1-methyl-3-indolyl)-6-benzoxazolyl]acetyl]-(4S)-fluoro-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid as a potent, orally active VLA-4 antagonist

Medicinal ChemistryPharmaceutical ScienceMedicineMechanism Of ActionPharmacological AgentPharmacotherapyActive Vla-4 AntagonistDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery