Serum levels of tumor necrosis factor-α (TNF-α), interleukin 6 (IL-6), and their soluble receptors in coal workers' pneumoconiosis

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

Tetsuya Taga, Masahiko Hibi, Yuuichi Hirata et al. · Cell · 1989 · 1.4K citations

Life Sciences, Immunology, Molecular Biology +14

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

Kimberly J. Van Zee, Tadahiko Kohno, E Fischer et al. · Proceedings of the National Academy of Sciences · 1992 · 852 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors.

Dan Aderka, Hartmut Engelmann, ‪Yasmin Maor‬‏ et al. · The Journal of Experimental Medicine · 1992 · 823 citations · Full text

Life Sciences, Immunology, Molecular Biology +11

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

Louis A. Tartaglia, R F Weber, Irene S. Figari et al. · Proceedings of the National Academy of Sciences · 1991 · 814 citations

Life Sciences, Immunology, Apoptosis +14

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

Herbert Tilg, Elizabeth Trehu, MB Atkins et al. · Blood · 1994 · 794 citations · Full text

Life Sciences, Immunology, Pharmacology +14