Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmacology +12

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

Kazuki N. Sugahara, Tambet Teesalu, Priya Karmali et al. · Cancer Cell · 2009 · 1.1K citations

Pharmacy, Oncology, Pharmaceutics +12

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.

Renata Pasqualini, Erkki Koivunen, Renate Kain et al. · PubMed · 2000 · 867 citations

Medicine, Oncology, Pharmacology +16

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent

Lihong Liu, Kaijin Xu, Huaying Wang et al. · Nature Nanotechnology · 2009 · 667 citations

Natural Sciences, Bioengineering, Biotechnology +14