Concepedia

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity

Marie‐Priscille Brun, Emmanuelle Braud, Delphine Angotti, Odile Mondésert, Muriel Quaranta, Matthieu Montès, Maria A. Miteva, Nohad Gresh, Bernard Ducommun, Christiane Garbay

Bioorganic & Medicinal Chemistry · 2005 · 59 citations · 39 references

DOI

Concepts

References

39

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano et al. · PubMed · 1993 · 1.9K citations

, , +14

Surflex:  Fully Automatic Flexible Molecular Docking Using a Molecular Similarity-Based Search Engine

Ajay N. Jain · Journal of Medicinal Chemistry · 2003 · 1.4K citations

, , +17

LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

C. M. Venkatachalam, Xiaoman Jiang, Tom Oldfield et al. · Journal of Molecular Graphics and Modelling · 2002 · 995 citations

, , +10

Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

Ulrich Strausfeld, Jean‐Claude Labbé, Didier Fesquet et al. · Nature · 1991 · 579 citations

, , +11

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

Konstantin Galaktionov, David Beach · Cell · 1991 · 508 citations

, , +17