Development of Novel Thiazolopyrimidines as CDC25B Phosphatase Inhibitors

Stéphanie Kolb, Odile Mondésert, Mary‐Lorène Goddard, +5

ChemMedChem

Tumor BiologyMedicinal ChemistryCdc25 ActivityThiazolopyrimidine FamilyChemoprevention Strategy +10

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity

Marie‐Priscille Brun, Emmanuelle Braud, Delphine Angotti, +7

Bioorganic & Medicinal Chemistry

Bioorganic ChemistryBiochemistryMedicineDrug DiscoveryNatural Sciences +7

Critical Impact of Peptidoglycan Precursor Amidation on the Activity of <scp>l,d</scp>‐Transpeptidases from <i>Enterococcus faecium</i> and <i>Mycobacterium tuberculosis</i>

Flora Ngadjeua, Emmanuelle Braud, Saidbakhrom Saidjalolov, +9

Chemistry - A European Journal

Bisubstrate analogues as structural tools to investigate m⁶A methyltransferase active sites

Stephanie Oerum, Marjorie Catala, Colette Atdjian, +8

RNA Biology

The catalytic mechanism of the RNA methyltransferase METTL3

Ivan Corbeski, Pablo Andrés Vargas-Rosales, R.K. Bedi, +9

eLife

Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase

Valérie Lobjois, Carine Froment, Emmanuelle Braud, +4

Biochemical and Biophysical Research Communications

Protein FunctionSignal TransductionSignaling PathwayBiochemistryMolecular Pathway +10

Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties

Emmanuelle Braud, Mary‐Lorène Goddard, Stéphanie Kolb, +6

Bioorganic & Medicinal Chemistry

BiochemistryCdc25 Phosphatase ActivityQuinolinedione InhibitorsMedicineAnti-cancer Agent +6

Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of <scp>l</scp>,<scp>d</scp>-Transpeptidase Ldt_Mt1 of <i>Mycobacterium tuberculosis</i> and the Stability toward Hydrolysis by β-Lactamase BlaC

Laura Iannazzo, Daria Soroka, Sébastien Triboulet, +8

Journal of Medicinal Chemistry

Diversity Oriented SynthesisBiosynthesisCarbapenem ClassBiochemistryNatural Sciences +13

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: Effect of dimerisation on phosphatase inhibition

Manal Sarkis, Diem Ngan Tran, Stéphanie Kolb, +4

Bioorganic & Medicinal Chemistry Letters

Phosphatase InhibitionBiochemistryMedicineRational Drug DesignDrug Development +4

Synthesis and combinatorial approach of the reactivity of 6- and 7-arylthieno[3,2-d][1,3]oxazine-2,4-diones

Francois‐Xavier Le Foulon, Emmanuelle Braud, Frédéric Fabis, +2

Tetrahedron

Combinatorial ChemistryCombinatorial ApproachEngineeringHeterocyclicOrganic Chemistry +4