Concepedia

LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII

Monica A. Stutz, David L. Shattuck, Melanie B. Laederich, Kermit L. Carraway, Colleen Sweeney

Oncogene · 2008 · 80 citations · 28 references

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References

28

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Ingo K. Mellinghoff, Maria Y. Wang, Igor Vivanco et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text

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The Enhanced Tumorigenic Activity of a Mutant Epidermal Growth Factor Receptor Common in Human Cancers Is Mediated by Threshold Levels of Constitutive Tyrosine Phosphorylation and Unattenuated Signaling

Hongyi Huang, Motoo Nagane, Candice K. Klingbeil et al. · Journal of Biological Chemistry · 1997 · 591 citations · Full text

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Ligand-Induced Transformation by a Noninternalizing Epidermal Growth Factor Receptor

Alan Wells, John Welsh, Cheri S. Lazar et al. · Science · 1990 · 412 citations

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Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

Robert Vassar, Elaine Fuchs · Genes & Development · 1991 · 410 citations · Full text

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

Paul H. Huang, Akitake Mukasa, Rudy Bonavia et al. · Proceedings of the National Academy of Sciences · 2007 · 389 citations · Full text

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