Melanie B. Laederich

The Leucine-rich Repeat Protein LRIG1 Is a Negative Regulator of ErbB Family Receptor Tyrosine Kinases

Melanie B. Laederich, Melanie Funes-Duran, Lily Yen et al. · Journal of Biological Chemistry · 2004 · 237 citations · Full text

Developmental Biology, Signal Transduction, Negative Regulator +14

LRIG1 Is a Novel Negative Regulator of the Met Receptor and Opposes Met and Her2 Synergy

David L. Shattuck, Jamie K. Miller, Melanie B. Laederich et al. · Molecular and Cellular Biology · 2006 · 125 citations · Full text

Invasive Growth, Met Receptor, Cancer Biology +20

The Interaction of Piasy with Trim32, an E3-Ubiquitin Ligase Mutated in Limb-girdle Muscular Dystrophy Type 2H, Promotes Piasy Degradation and Regulates UVB-induced Keratinocyte Apoptosis through NFκB

Amador Albor, Sally El-Hizawi, Elizabeth J. Horn et al. · Journal of Biological Chemistry · 2006 · 83 citations · Full text

Apoptosis, Cell Death, Piasy Ubiquitination +17

LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII

Monica A. Stutz, David L. Shattuck, Melanie B. Laederich et al. · Oncogene · 2008 · 80 citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +3

Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors

Krishna Midde, Nicolas Aznar, Melanie B. Laederich et al. · Proceedings of the National Academy of Sciences · 2015 · 48 citations · Full text