Oxidation State-Specific Fluorescent Method for Palladium(II) and Platinum(IV) Based on the Catalyzed Aromatic Claisen Rearrangement

Abstract

Contamination of active pharmaceutical ingredients and healthcare products with oxidized forms of palladium and platinum are important problems. We report a convenient fluorogenic probe based on the catalyzed aromatic Claisen rearrangement capable of detecting Pd II and Pt IV . Using this probe, we can fluorescently detect Pd II in functionalized organic compounds and Pt IV in Pt 0 -water without sample pretreatment. This method may find broad applications in the pharmaceutical industry, the environment, and Pd/Pt quality control.