Regiospecific horse liver alcohol dehydrogenase-catalyzed oxidations of some bishydroxycyclohexanes

Abstract

Horse liver alcohol dehydrogenase has been shown to be effective in catalyzing regiospecific oxidations of only the primary alcohol functions of several cyclohexane substrates possessing both primary and secondary alcohol substituents. The reactions, which were all performed on a preparative scale, were also enantioselective in some cases.