Immunity · 1994 · 300 citations · 55 references
Life SciencesImmunologyMolecular BiologyCell DifferentiationCellular ImmunologyDevelopmental ImmunologyAntigen Receptor Gene RearrangementLymphocyte DevelopmentT Cell BiologyT Cell DevelopmentT Cell DifferentiationThymic DevelopmentT Cell Receptor Beta Chain RearrangementT-cell Receptor Beta Chain GeneticsThymic T Cell DevelopmentThymic T-cell Receptor Gene RearrangementThymocyte Maturation
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RAG-1-deficient mice have no mature B and T lymphocytes
Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations
Life Sciences, Genetics, Immunology +13
Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages
Peter Mombaerts, Alan R. Clarke, Michael A. Rudnicki et al. · Nature · 1992 · 1.1K citations
Life Sciences, Genetics, Immunology +16
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain
Andrew C. Chan, Makio Iwashima, Christoph W. Turck et al. · Cell · 1992 · 1K citations
Profound block in thymocyte development in mice lacking p56lck
Thierry Jo Molina, Kenji Kishihara, David P. Siderovski et al. · Nature · 1992 · 966 citations