T cell receptor β chain gene rearrangement and selection during thymocyte development in adult mice

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.1K citations · Full text

Dna, Engineering, Dna Analysis +20

RAG-1-deficient mice have no mature B and T lymphocytes

Peter Mombaerts, John Iacomini, Randall S. Johnson et al. · Cell · 1992 · 2.9K citations

Mature B, Autoimmune Disease, Lymphocyte Development +4

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

Peter Mombaerts, Alan R. Clarke, Michael A. Rudnicki et al. · Nature · 1992 · 1.1K citations

Lymphocyte Development, Immune Cell Development, Genetics +12

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

Andrew C. Chan, Makio Iwashima, Christoph W. Turck et al. · Cell · 1992 · 1K citations

Protein Function, Signal Transduction, Molecular Physiology +12

Profound block in thymocyte development in mice lacking p56lck

Thierry Jo Molina, Kenji Kishihara, David P. Siderovski et al. · Nature · 1992 · 961 citations

Knockout Mouse, Signal Transduction, Cell Regulation +8