Hormone and Metabolic Research · 1976 · 32 citations · 0 references
Life SciencesBiochemistryNutritional SciencesMetabolic PhysiologyMetabolismNutritional BiochemistryFatty Acid ChemistryFatty Acid MetabolismFatty Acid OxidationLipid MetabolismTriacylglycerol MetabolismTriglyceride MetabolismDietary Fat EffectsDietary Fatty Acid CompositionHepatic Triacylglycerol MetabolismHepatic Triglyceride MetabolismLong-chain Fatty Acid MetabolismMedium-chain Fatty Acid MetabolismMitochondrial Fatty Acid MetabolismMitochondrial Redox State
The influence of a single load of medium chain triglycerides (MCT) or long chain triglycerides (LCT) on different intermediary metabolites of the rat liver was studied. Resultes showed that acetyl-CoA increased more after MCT than after LCT. MCT are more ketogenic than LCT. Mitochondrial and cytoplasmic redox state was greatly reduced after MCT. It is particularly interesting to note that MCT produced an increase in malate and citrate levels, whereas LCT had only a minor influence on these substances.