LRRK2 P755L variant in sporadic Parkinson’s disease

Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

Alexander Zimprich, Saskia Biskup, Petra Leitner et al. · Neuron · 2004 · 3K citations · Full text

Mendelian Disorder, Genetic Disorder, Parkinson Disease +5

Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

Coro Paisán‐Ruíz, Shushant Jain, E. Whitney Evans et al. · Neuron · 2004 · 2.4K citations · Full text

Neurodegenerative Diseases, Genetic Disorder, Parkinson Disease +9

A common LRRK2 mutation in idiopathic Parkinson's disease

William P. Gilks, Patrick M. Abou‐Sleiman, Sonia Gandhi et al. · The Lancet · 2005 · 777 citations

Mendelian Disorder, Parkinson Disease, Pathology +3

A new locus for Parkinson's disease (<i>PARK8</i>) maps to chromosome 12p11.2–q13.1

Manabu Funayama, Kazuko Hasegawa, Hisayuki Kowa et al. · Annals of Neurology · 2002 · 656 citations

Genetics, Disease Gene Identification, Genome-wide Association Study +16

Kinase activity of mutant LRRK2 mediates neuronal toxicity

Wanli W. Smith, Zhong Pei, Haibing Jiang et al. · Nature Neuroscience · 2006 · 619 citations

Signal Transduction, Molecular Neuroscience, Cell Death +6