Concepedia
Cancer Chemotherapy and Pharmacology · 2010 · 70 citations · 33 references
BiochemistryOncogenic AgentMedicineLipid PeroxidationCellular DnaProoxidant BreakageReactive Oxygen SpecieOncologyCell BiologyRedox BiologyCancer ResearchChemotherapeutic ActionOxidative Stress
33
Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing
Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis · 2000 · 4.8K citations
Genotoxicity Test Procedures, Genetic Testing, Dna Damage +20
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues
Qi Chen, Michael Graham Espey, Murali C. Krishna et al. · Proceedings of the National Academy of Sciences · 2005 · 1.1K citations · Full text
Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use
Sebastian J. Padayatty, He Sun, Yaohui Wang et al. · Annals of Internal Medicine · 2004 · 953 citations
Vitamin C Pharmacokinetics, Oncology, Pharmacokinetic Modeling +13
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Qi Chen, Michael Graham Espey, Andrew Y. Sun et al. · Proceedings of the National Academy of Sciences · 2008 · 843 citations · Full text
Ascorbic Acid, Pharmacologic Doses, Glioma +14
High-Dose Vitamin C versus Placebo in the Treatment of Patients with Advanced Cancer Who Have Had No Prior Chemotherapy
Charles G. Moertel, Thomas R. Fleming, Edward T. Creagan et al. · New England Journal of Medicine · 1985 · 622 citations