Murali C. Krishna

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

Qi Chen, Michael Graham Espey, Murali C. Krishna et al. · Proceedings of the National Academy of Sciences · 2005 · 1.1K citations · Full text

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

Qi Chen, Michael Graham Espey, Andrew Y. Sun et al. · Proceedings of the National Academy of Sciences · 2008 · 843 citations · Full text

Ascorbic Acid, Pharmacologic Doses, Glioma +14

Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.

David A. Wink, Ingeborg Hanbauer, Murali C. Krishna et al. · Proceedings of the National Academy of Sciences · 1993 · 775 citations

Ischemia Reperfusion, Nitric Oxide, Lipid Peroxidation +18

Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.

Periannan Kuppusamy, Haiquan Li, Govindasamy Ilangovan et al. · PubMed · 2002 · 688 citations

Oncologic Imaging, Tumor Redox Status, Redox Status +22

Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid <i>in vivo</i>

Qi Chen, Michael Graham Espey, Andrew Y. Sun et al. · Proceedings of the National Academy of Sciences · 2007 · 658 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Experimental Pharmacology +19