Concepedia

Tissue distribution and depletion kinetics of bortezomib and bortezomib-related radioactivity in male rats after single and repeated intravenous injection of 14C-bortezomib

Alex Hemeryck, R Geerts, Johan Monbaliu, Stephan Hassler, Tom Verhaeghe, Luc Diels, Willy Verluyten, Ludy van Beijsterveldt, Rao N. V. S. Mamidi, Cor Janssen,

Cancer Chemotherapy and Pharmacology · 2007 · 54 citations · 6 references

DOI

Concepts

References

6

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

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Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

Kevin St. P. McNaught, Daniel P. Perl, Anna‐Liisa Brownell et al. · Annals of Neurology · 2004 · 543 citations

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Approval Summary for Bortezomib for Injection in the Treatment of Multiple Myeloma

Peter Bross, Robert C. Kane, Ann T. Farrell et al. · Clinical Cancer Research · 2004 · 340 citations · Full text

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Severe pulmonary complications in Japanese patients after bortezomib treatment for refractory multiple myeloma

Shigesaburo Miyakoshi, Masahiro Kami, Koichiro Yuji et al. · Blood · 2006 · 167 citations · Full text

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RELATIVE CONTRIBUTIONS OF THE FIVE MAJOR HUMAN CYTOCHROMES P450, 1A2, 2C9, 2C19, 2D6, AND 3A4, TO THE HEPATIC METABOLISM OF THE PROTEASOME INHIBITOR BORTEZOMIB

Vinita Uttamsingh, Chuang Lu, Gerald T. Miwa et al. · Drug Metabolism and Disposition · 2005 · 137 citations

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