American College of Clinical Pharmacology Position Statement on the Use of Microdosing in the Drug Development Process

Use of microdosing to predict pharmacokinetics at the therapeutic dose: Experience with 5 drugs

Graham Lappin, W. Kuhnz, R. Jochemsen et al. · Clinical Pharmacology & Therapeutics · 2006 · 242 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +13

Guidance for Industry, Investigators, and Reviewers: Exploratory IND Studies

Biotechnology Law Report · 2006 · 113 citations

Public Health, Quality Management, Experimental Design +9

A Proposal for Radical Changes in the Drug-Approval Process

Alastair J.J. Wood · New England Journal of Medicine · 2006 · 113 citations

Pharmacy, Pharmaceutical Policy, Drug Approval Processes +10

Current perspectives of 14 C-isotope measurement in biomedical accelerator mass spectrometry

Graham Lappin, R. Colin Garner · Analytical and Bioanalytical Chemistry · 2004 · 78 citations · Full text

Natural Sciences, Biochemistry, Chemistry +11

Comparison of the Absorption of Micronized (Daflon 500® mg) and Nonmicronized 14C‐diosmin Tablets After Oral Administration to Healthy Volunteers by Accelerator Mass Spectrometry and Liquid Scintillation Counting

R. Colin Garner, John Garner, S A Gregory et al. · Journal of Pharmaceutical Sciences · 2002 · 78 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +14