OPA1, associated with autosomal dominant optic atrophy, is widely expressed in the human brain

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

Cécile Delettre, Guy Lenaers, Jean‐Michel Griffoin et al. · Nature Genetics · 2000 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +13

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Christiane Alexander, Marcela Votruba, Ulrike E. A. Pesch et al. · Nature Genetics · 2000 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +9

Local distribution of microglia in the normal adult human central nervous system differs by up to one order of magnitude

Michel Mittelbronn, Klaus Dietz, Hermann J. Schluesener et al. · Acta Neuropathologica · 2001 · 482 citations

Life Sciences, Neurobiology, Neuroscience +10

The human dynamin‐related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter‐membrane space

Aurélien Olichon, Laurent J. Emorine, Eric Descoins et al. · FEBS Letters · 2002 · 413 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Mutation spectrum and splicing variants in the OPA1 gene

Cécile Delettre, Jean‐Michel Griffoin, Josseline Kaplan et al. · Human Genetics · 2001 · 380 citations

Life Sciences, Genetics, Molecular Genetics +13