A modified preparation (LMK03) of the oriental medicine Jangwonhwan reduces Aβ1–42 level in the brain of Tg-APPswe/PS1dE9 mouse model of Alzheimer disease

Global prevalence of dementia: a Delphi consensus study

Cleusa P. Ferri, Martin Prince, Carol Brayne et al. · The Lancet · 2005 · 5.3K citations · Full text

Medicine, Geriatric Medicine, Neurology +11

Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease

Sudha Seshadri, Alexa Beiser, Jacob Selhub et al. · New England Journal of Medicine · 2002 · 3.2K citations · Full text

Medicine, Geriatric Medicine, Nutritional Sciences +15

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.2K citations

Life Sciences, Neurology, Neuroscience +14

Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial

S. Gilman, M. Köller, R. S. Black et al. · Neurology · 2005 · 1.3K citations

Medicine, Neurology, Neuroscience +17

Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

Yi Luo, Brad Bolon, Steve Kahn et al. · Nature Neuroscience · 2001 · 994 citations

Life Sciences, Genetics, Neuroscience +16