Lysophosphatidylcholine as a possible second messenger synergistic to diacylglycerol and calcium ion for T-lymphocyte activation

Inositol trisphosphate, a novel second messenger in cellular signal transduction

Michael J. Berridge, Robin F. Irvine · Nature · 1984 · 6.1K citations

Signal Transduction, Biochemistry, Natural Sciences +9

Signaling through phosphatidylcholine breakdown.

John H. Exton · Journal of Biological Chemistry · 1990 · 1.4K citations · Full text

Proteinlipid Interaction, Lipid Movement, Cellular Physiology +18

The role of protein kinase C in transmembrane signaling by the T cell antigen receptor complex. Effects of stimulation with soluble or immobilized CD3 antibodies.

B Manger, Arthur Weiss, John B. Imboden et al. · The Journal of Immunology · 1987 · 154 citations

Adaptive Immune System, Immunology, Immunologic Mechanism +23

Diacylglycerol kinase from pig brain. Purification and phospholipid dependencies.

Hideo Kanoh, H Kondoh, Takashi Ono · Journal of Biological Chemistry · 1983 · 135 citations · Full text

Human T cell activation by phorbol esters and diacylglycerol analogues.

Nicola Berry, Katsuhiko Ase, Ushio Kikkawa et al. · The Journal of Immunology · 1989 · 83 citations · Full text