Cryptotanshinione Inhibits β-Amyloid Aggregation and Protects Damage from β-Amyloid in SH-SY5Y Cells

Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways

Gal Bitan, Marina Kirkitadze, Aleksey Lomakin et al. · Proceedings of the National Academy of Sciences · 2002 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Inhibition of Mitochondrial Respiration

Hélène Pelicano, Feng Li, Yan Zhou et al. · Journal of Biological Chemistry · 2003 · 489 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

Scott L. Crick, Guojun Bu, Carl Frieden et al. · Proceedings of the National Academy of Sciences · 2009 · 429 citations

Life Sciences, Biochemistry, Neuroscience +17

Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis

JoAnne McLaurin, Roxana Cecal, Meredith E. Kierstead et al. · Nature Medicine · 2002 · 416 citations

Pharmacy, Biochemistry, Pharmacology +12

Fibrillar Amyloid-β Peptides Activate Microglia via TLR2: Implications for Alzheimer’s Disease

Malabendu Jana, Carlos A. Palencia, Kalipada Pahan · The Journal of Immunology · 2008 · 329 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17