Impaired learning with enhanced hippocampal long‐term potentiation in PTPδ‐deficient mice

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Richard Morris, Eric Anderson, Gary Lynch et al. · Nature · 1986 · 3.6K citations

Life Sciences, Neuroscience, Pharmacology +15

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

András Nagy, Janet Rossant, Roland Nagy et al. · Proceedings of the National Academy of Sciences · 1993 · 2.4K citations

Life Sciences, Biology, Genetics +16

The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory

Joe Z. Tsien, Patricio T. Huerta, Susumu Tonegawa · Cell · 1996 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Dendritic spine changes associated with hippocampal long-term synaptic plasticity

Florian Engert, Tobias Bonhoeffer · Nature · 1999 · 1.7K citations

Life Sciences, Neurobiology, Neuroscience +14

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

Alcino J. Silva, Charles F. Stevens, Susumu Tonegawa et al. · Science · 1992 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +17