FokI requires two specific DNA sites for cleavage

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

Life Sciences, Biotechnology, Molecular Biology +15

<i>Fok</i> I dimerization is required for DNA cleavage

Jurate Bitinaite, David A. Wah, Aneel K. Aggarwal et al. · Proceedings of the National Academy of Sciences · 1998 · 488 citations · Full text

Pharmacy, Genetics, Molecular Biology +17

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

Jarrett Smith · Nucleic Acids Research · 2000 · 421 citations

Life Sciences, Biochemistry, Molecular Biology +16

Structure of Bam HI Endonuclease Bound to DNA: Partial Folding and Unfolding on DNA Binding

Matthew Newman, Teresa E. Strzelecka, Lydia F. Dorner et al. · Science · 1995 · 299 citations

Life Sciences, Biochemistry, Molecular Biology +17

Structure of the multimodular endonuclease FokI bound to DNA

David A. Wah, Joel A. Hirsch, Lydia F. Dorner et al. · Nature · 1997 · 267 citations

Life Sciences, Biochemistry, Molecular Biology +8