Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

Joachim Messing, Jeffrey Vieira · Gene · 1982 · 2.9K citations

Life Sciences, Biotechnology, Molecular Biology +9

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

John W. Newport, Marc W. Kirschner · Cell · 1982 · 1.7K citations

Life Sciences, Biology, Developmental Biology +17

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

Michael R. Lerner, Joan A. Steitz · Proceedings of the National Academy of Sciences · 1979 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

Colin Dingwall, Stephen V. Sharnick, Ronald A. Laskey · Cell · 1982 · 552 citations

Life Sciences, Cell Biology, Molecular Biology +11